Anesthesia recommendations in patients suffering from Arthrogryposis multiplex congenita

Disease name: Arthrogryposis multiplex congenita ICD 10: Q74.32 Synonyms: Arthrogryposis, Amyoplasia Congenita, Congenital Arthromyodysplasia, GuérinStern syndrome, Myodystrophia Fetalis Deformans AMC is the clinical description of a congenital syndrome with an estimated incidence of 1:3000-10,000 [25,30,38]. Already within the uterus, the movement frequency of the foetus is reduced due to multiple – mostly symmetrical – joint contractures. Primarily, the great joints of extremities, the spine [12] but also the otolaryngologic region [10,11] are affected with varying severity. Furthermore, a reduced muscle mass and a merely developed subcutaneous tissue are notable. During growth, numerous deformities are generated. Other organ systems can be involved (CNS, cardiovascular system, lungs, gastrointestinal tract, urogenital tract, abdominal wall). In most cases, patients develop normal intelligence.